AB086. 139. Long-term follow-up of patients treated with Nizoral shampoo for chronic, recalcitrant otitis externa
H&N/ENT Session

AB086. 139. Long-term follow-up of patients treated with Nizoral shampoo for chronic, recalcitrant otitis externa

Odharna Ní Dhomhnalláin, Caoimhe A. Byrne, Abdelrahman E. M. Ezzat, John E. Fenton

Department of Surgery, University Hospital Limerick, Limerick, Ireland


Background: Otitis externa (OE) is a common condition, with a prevalence of 1%. While the majority of cases are seen in the community, with rapid resolution following conventional topical therapies, a small fraction persist, requiring review by otorhinolaryngologists. Novel therapies, including topical immunomodulators like Tacrolimus, are now employed in these recalcitrant cases. In our institution, a cohort of such patients have been successfully treated with a combination of Nizoral, a Ketoconazole-containing shampoo, and topical Tacrolimus. We now report their long-term results.

Methods: These patients were retrospectively identified through a search of an individual surgeon’s clinic letters (n=24). Nizoral shampoo was used twice-weekly for 4 weeks, with instructions for nail care and maintenance therapy. Using their clinic letters, along with their charts, the self-reported symptoms, demographics, microbiology reports, number of out-patient appointments and clinical findings were recorded.

Results: Among these patients with recalcitrant chronic OE, one reported recurrence. The remaining patients are awaiting follow up or have deigned to attend.

Conclusions: Nizoral, in combination with Tacrolimus, has, in our small cohort, demonstrated long-term efficacy in the treatment of unresponsive cases of Chronic Otitis Externa. It should be considered as an adjunct to Tacrolimus, particularly when involvement of seborrhoeic dermatitis is considered as a contributing factor.

Keywords: Nizoral; otitis externa; tacrolimus


doi: 10.21037/map.2018.AB086


Cite this abstract as: Ní Dhomhnalláin O, Byrne CA, Ezzat AE, Fenton JE. Long-term follow-up of patients treated with Nizoral shampoo for chronic, recalcitrant otitis externa. Mesentery Peritoneum 2018;2:AB086. doi: 10.21037/map.2018.AB086